Selective syntheses of no-carrier-added 2- and 3-[18F]fluorohalopyridines through the radiofluorination of halopyridinyl(4′-methoxyphenyl)iodonium tosylates
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چکیده
منابع مشابه
Syntheses of mGluR5 PET radioligands through the radiofluorination of diaryliodonium tosylates.
3-Fluoro-1-((thiazol-4-yl)ethynyl)benzenes constitute an important class of high-affinity metabotropic glutamate subtype 5 receptor (mGluR5) ligands, some of which have been labeled with fluorine-18 (t(1/2) = 109.7 min), to provide radioligands for molecular imaging of brain mGluR5 in living animal and human subjects with positron emission tomography (PET). Labeling in the 3-fluoro position of ...
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2012
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c2cc35005j